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Upstream Process Development Associate

Company: Kelly Services
Location: Olney
Posted on: April 9, 2021

Job Description:

Upstream Process Development AssociateGaithersburg, MDContract-to-Hire OpportunityFull-Time, Dayshift--Kelly Science & Clinical is interviewing and hiring immediately for an experienced upstream manufacturing professional with a leader in gene delivery and gene expression technology. This position is a great fit for someone with previous experience with stirred-tank bioreactors, preferably single-use, who is looking to continue growing long-term with an innovative and leading team.Responsibilities

  • Support the development, characterization, and tech transfer of process to manufacture purified lentiviral vectors for use in pre-clinical and clinical gene therapy products
  • Support production and characterization of lentiviral vectors using adherent and suspension-based production platforms
  • Carry out all aspects of upstream vector production
  • Order necessary supplies
  • Maintain laboratory equipment and space
  • Prepare media and buffers
  • Train team members as needed
  • Track and communicate data and document/organize towards efficient program
  • Produce lentiviral vectors in a cross-functional team
  • Other duties as assignedQualifications
    • Degree in the life sciences with at least 2 years of relevant experience; or equivalent combination of education and experience.
    • Previous biotech industry experience is preferred, specifically in the fields of gene therapy and virology
    • Adherent and/or suspension mammalian cell culture, transfection, and harvest of viral vectors and/or antibodies using aseptic techniques.
    • Strong experience utilizing stirred-tank bioreactors in the production of viral vectors and/or antibodies. Disposable and single use stirred-tank bioreactor experience preferred.
    • An understanding of DO/pH control loops, PID settings, and scale up and scale down parameters.
    • Having Good Documentation Practices and timely completion of Batch Production Records.
    • Practical knowledge in a range of bioprocess analytical techniques, such as but not limited to, cell-based assays, flow cytometry, qPCR, Western Blot analysis, and ELISA.
    • Superb documentation and organizational skills, capable of providing summaries and generating reports to support technical transfer to Manufacturing as well as process qualification
    • Ability to work in a team and collaborative environment
    • Highly proficient in the use of Microsoft Office products
    • Weekend and holiday work may be required to maintain cell culture vessels or set up assays.
    • Strong organizational skills and ability to prioritize multiple projects to completion
    • Experience with late-stage product development, application of QbD principles, as well as statistical design of experiments with JMP software is a plus.--Why Kelly--?Kelly Science & Clinical is your connection to premier scientific and clinical companies looking to hire talented people just like you. Every day, we match science professionals with dream jobs that fit their skills and interests-it's the way we think job searching should be. Nearly 100 percent of our science recruiters have a professional background/education in science, so we know a thing or two about the science market and how to get you noticed.About Kelly--At Kelly, we're always thinking about what's next and advising job seekers on new ways of working to reach their full potential. In fact, we're a leading advocate for temporary/nontraditional workstyles, because we believe they allow flexibility and tremendous growth opportunities that enable a better way to work and live. Connecting great people with great companies is what we do best, and our employment opportunities span a wide variety of workstyles, skill levels, and industries around the world. Kelly is an equal opportunity employer committed to employing a diverse workforce, including, but not limited to, minorities, females, individuals with disabilities, protected veterans, sexual orientation, gender identity. Equal Employment Opportunity is The Law.]]

Keywords: Kelly Services, Olney , Upstream Process Development Associate, Other , Olney, Maryland

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